How Does Diffusion Actually Move Substances Without Energy?
Diffusion
The net movement of particles from an area of higher concentration to an area of lower concentration, down a concentration gradient, as a result of random movement.
- Diffusion is a passive process, it doesn't require energy input from the cell (no ATP needed).
- It works because of the concentration gradient:
- More particles on one side = more random movement on that side.
- More movement = more particles moving outward.
- Fewer particles on the other side = fewer particles moving back.
- Net movement is therefore from high to low concentration.
- This will continue until equilibrium is reached (equal concentration everywhere).
- Once equilibrium is reached, the concentration gradient will no longer exist.
- Diffusion doesn't mean all particles move in one direction.
- Individual particles will still move randomly in all directions.
- It's just the case that more will move from high to low than the reverse.
- Imagine two rooms connected by a door.
- Room A has 100 people, Room B has 10 people.
- People walk randomly through the door in both directions, but because Room A is more crowded, more people happen to walk from A to B than from B to A.
- Eventually, both rooms have 55 people.
- No one forced anyone to move - it just happened through random movement.
- "Passive" doesn't mean slow.
- Diffusion can be very fast over short distances - oxygen diffuses from your lungs to your blood in less than a second.
Why Is Diffusion Fast in Some Places and Slow in Others?
Several factors affect how fast diffusion occurs:
Concentration gradient
- Steeper gradient = faster diffusion:
- Large difference in concentration = more net movement.
- Small difference in concentration = less net movement.
- As diffusion proceeds, the gradient decreases:
- The difference gets smaller over time.
- Diffusion slows down as it approaches equilibrium.
- If you sprayed a lot of perfume (steep gradient), you'll smell it across the room quickly.
- If you only sprayed a tiny amount (shallow gradient) , it'll take longer to spread.
Temperature
- Higher temperature = faster diffusion:
- Particles have more kinetic energy.
- They move faster and collide more frequently.
- More collisions = faster spreading.
- Lower temperature = slower diffusion:
- Particles have less kinetic energy.
- They move slower with fewer collisions.
This is why it's quicker to make your tea with hot water versus cold water
Surface Area
- Larger surface area = faster diffusion:
- More space for particles to cross.
- More particles can move simultaneously.
- Cells and organisms increase surface area for diffusion:
- Lungs have millions of tiny air sacs (alveoli) - massive surface area.
- Small intestine has millions of tiny projections (villi) - increases surface area for nutrient absorption.
- Root hair cells have long projections - more surface area for water absorption.
- A crushed sugar cube dissolves faster than a whole cube even if it's the same amount of sugar.
- But since crushed sugar has much more surface area exposed to water, diffusion will occur much faster.
Distance
- Shorter distance = faster diffusion:
- Particles reach their destination quicker.
- Diffusion is only efficient over short distances (typically less than 1mm).
- Longer distance = much slower diffusion:
- Diffusion time increases exponentially with distance.
- This is why large organisms need transport systems (blood, xylem, phloem) - diffusion alone is too slow.
- Capillary walls are only one cell thick (about 1 micrometer).
- Oxygen diffuses from blood to tissues in a fraction of a second.
- If the wall were thicker, diffusion would be too slow to keep tissues alive.
Size of Molecules
- Smaller molecules = faster diffusion:
- Less mass means easier to move.
- Can slip between other particles more easily.
- Larger molecules = slower diffusion:
- More mass means more inertia.
- More likely to collide and bounce back.
- This is why cells are small.
- If cells were huge, diffusion would be too slow to supply the center with oxygen and nutrients.
- Most cells are 10-30 micrometers across - the perfect size for efficient diffusion.
- Oxygen molecules (O₂) are tiny and diffuse very quickly through cell membranes.
- Glucose molecules are much larger and diffuse more slowly, often needing transport proteins to help them cross.
- The eAssessment questions will often ask you to explain adaptations for diffusion.
- Make sure to always link structure to function using the factors.
- Why does diffusion not require energy (ATP)?
- List three factors that increase the rate of diffusion.
- Why does a concentration gradient get smaller over time during diffusion?
- Explain why single-celled organisms can rely on diffusion but humans cannot.