So What's In a Cell?
Understanding what each organelle actually does will explain to you why cells are built the way they are.
Organelles
Membrane-bound or non-membrane-bound structures within a cell that perform specific, specialized functions essential for cellular processes.
Nucleus
Nucleus
A membrane-bound organelle containing chromosomes (DNA) and a nucleolus, which controls cellular activities by regulating gene expression and protein synthesis.
- Think of it as the cell's control center or headquarters.
- It stores all the genetic instructions (DNA) for making proteins.
- Without a nucleus, the cell can't make new proteins or divide to produce new cells.
Mitochondria
Mitochondria
Double-membrane-bound organelles that are the site of aerobic cellular respiration, converting glucose and oxygen into ATP (usable energy).
- Think of them as the cell's power stations.
- They break down glucose using oxygen to release energy in a form cells can actually use (ATP).
- More mitochondria = more ATP = more energy available for cell activities.
- Don't assume having one mitochondrion is enough.
- Cells need hundreds or thousands depending on their energy needs.
Ribosomes
Ribosomes
Small non-membrane-bound organelles composed of ribosomal RNA (rRNA) and proteins, which are the site of protein synthesis through translation.
- These are your protein-making factories.
- They read instructions from DNA (via mRNA) and assemble amino acids into proteins.
- More ribosomes = faster and more protein production.
Chloroplasts
Chloroplasts
Double-membrane-bound organelles found in plant cells and algae containing chlorophyll, which are the site of photosynthesis.
- Chloroplasts are like solar panels that capture light energy.
- They convert light energy, carbon dioxide, and water into glucose (food) and oxygen.
The green pigment chlorophyll absorbs light and is what gives plants their green color.
Remember chloroplasts will not be found in animal cells, only plant cells.
Cell membrane
Cell membrane
A selectively permeable phospholipid bilayer with embedded proteins that surrounds all cells, controlling the movement of substances in and out of the cell.
- The cell membrane is like your body's bouncer or security guard.
- It allows useful molecules (oxygen, nutrients) to enter while keeping harmful substances out.
- It also controls what waste products leave the cell.
Cell wall
Cell wall
A rigid structural layer composed primarily of cellulose (in plants) that surrounds the cell membrane, providing mechanical support and protection.
- This is like the walls of a castle for plants, and is what gives plant cells their characteristic rectangular shape.
- Prevents the cell from bursting when water enters by osmosis.
Vacuole
Vacuole
A membrane-bound organelle filled with cell sap (water, dissolved sugars, salts, and pigments) that maintains turgor pressure in plant cells.
- The vacuole functions like a water balloon.
- It will push outward against the cell wall to keep the plant cell rigid and the plant upright.
- The sap inside it (the water inside the balloon) then acts as a storage unit with nutrients, waste products, and pigments (like those in flower petals).
Cytoplasm
Cytoplasm
The aqueous, gel-like substance enclosed by the cell membrane that contains all organelles, dissolved nutrients, enzymes, and where many metabolic reactions occur.
- Lastly, the cytoplasm is like the factory floor of all the organelles within the cell.
- It's mostly water with dissolved substances floating in it.
- Chemical reactions happen here, and organelles are suspended in it.
How Do Organelles Control What a Cell Can Do?
The combination of organelles determines what the cell can do overall.
- This is why more of an organelle = better at that function:
- Loads of mitochondria = good at releasing energy (e.g., muscle cells).
- Loads of ribosomes = good at making proteins (e.g., cells that produce hormones).
- Loads of chloroplasts = good at photosynthesis (e.g., leaf palisade cells).
- No organelle = can't do that function:
- Animal cells have no chloroplasts, so they can't photosynthesize.
- Red blood cells have no nucleus, so they can't divide or make new proteins.
- Cell = factory.
- Nucleus = manager's office.
- Mitochondria = power generators.
- Ribosomes = assembly lines.
- Cell membrane = security.
How Do Cells Become Specialized for Different Functions?
Differentiation
The process by which a cell becomes specialized to perform a specific function, involving changes in structure and which genes are expressed.
- All cells in your body start as copies from the same fertilized egg, and eventually specialize through differentiation.
- Once differentiated, most cells can't change back.
- This starts during embryo development and continues in some tissues throughout life.
- However, not all cells become differentiated, these undifferentiated cells are known as stem cells.
Stem cells
Unspecialized cells that can divide and differentiate into many different specialized cell types.
Example
- Found in embryos (embryonic stem cells) and some adult tissues (adult stem cells).
- Can still become different cell types.
- Used by the body to replace damaged cells and for growth.
Structural changes during differentiation
- Some cells gain organelles:
- Muscle cells develop lots of mitochondria.
- Palisade cells develop lots of chloroplasts.
- Protein-secreting cells develop lots of ribosomes.
- Some cells lose organelles:
- Red blood cells lose their nucleus to make room for hemoglobin.
- Red blood cells also lose their mitochondria (they don't need to respire as much).
- Cell shape changes:
- Nerve cells grow extremely long extensions (axons).
- Root hair cells develop long projections.
- Muscle cells become elongated and cylindrical.
- Special structures develop:
- Sperm cells grow a tail (flagellum) for swimming.
- Ciliated epithelial cells grow tiny hair-like projections (cilia).
- Muscle cells develop specialized features for contraction:
- Multiple cells fuse together to create longer, stronger contractions.
- Mitochondria increase to 1000-2000 per cell for constant ATP supply during repeated contractions.
- Protein filaments (actin and myosin) develop to generate contracting force.
- Cells become elongated so they can shorten significantly when contracting.
How Do Organelles Work Together?
Organelles don't work in isolation, they cooperate to carry out complex processes.
- The nucleus, ribosomes, and mitochondria form a key partnership:
- Nucleus provides instructions from DNA.
- Ribosomes use those instructions to make proteins.
- Mitochondria provide energy (ATP) for these processes.
- Making a protein requires multiple organelles:
- Nucleus sends out instructions.
- Ribosomes build the protein.
- Mitochondria supply the energy needed.
- Cell membrane can release the protein if needed.
- Examiners always want to see you understand the cooperation between organelles.
- Never simply list out the functions of organelles in isolation.
- What is the function of mitochondria in a cell?
- Why can't animal cells carry out photosynthesis?
- What happens to a red blood cell's nucleus during differentiation and why?
- Which three organelles work together to make and secrete a protein?
- Name two types of cells that have large numbers of ribosomes.
- What is the difference between a differentiated cell and a stem cell?