IB Biology Topic C1.2.9 Conversion of Pyruvate to Lactate Revision Notes (HL)

IB Biology Topic C1.2.9 Conversion of Pyruvate to Lactate Revision Notes (HL) | RevisionDojo

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Pyruvate Is Reduced to Lactate to Regenerate NAD⁺, Not to Make ATP

Glycolysis needs NAD⁺ to keep running, but the cell holds only a limited supply (see C1.2.8).
Without oxygen the electron transport chain cannot regenerate NAD⁺, so glycolysis would stall.
To fix this, pyruvate acts as an electron acceptor, so NAD⁺ can be recycled.

Analogy

Picture glycolysis as an assembly line producing ATP.
NAD acts like a conveyor belt carrying electrons to keep the line moving.
Without oxygen the belt jams unless lactate production clears it.

Lactate Dehydrogenase Converts Pyruvate to Lactate and Recycles NAD⁺

The enzyme lactate dehydrogenase catalyses the conversion of pyruvate to lactate.

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Pyruvate Is Reduced to Lactate to Regenerate NAD⁺, Not to Make ATP

Glycolysis needs NAD⁺ to keep running, but the cell holds only a limited supply (see C1.2.8).
Without oxygen the electron transport chain cannot regenerate NAD⁺, so glycolysis would stall.
To fix this, pyruvate acts as an electron acceptor, so NAD⁺ can be recycled.

Analogy

Picture glycolysis as an assembly line producing ATP.
NAD acts like a conveyor belt carrying electrons to keep the line moving.
Without oxygen the belt jams unless lactate production clears it.

Lactate Dehydrogenase Converts Pyruvate to Lactate and Recycles NAD⁺

The enzyme lactate dehydrogenase catalyses the conversion of pyruvate to lactate.

Definition

Paywall

(on a website) an arrangement whereby access is restricted to users who have paid to subscribe to the site.

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

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Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam quis nostrud exercitation.

Excepteur sint occaecat cupidatat non proident

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Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
Duis aute irure dolor in reprehenderit in voluptate velit esse cillum.

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A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

IB Biology Topic C1.2.9: Conversion of Pyruvate to Lactate Notes

A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

Pyruvate Is Reduced to Lactate to Regenerate NAD⁺, Not to Make ATP

Lactate Dehydrogenase Converts Pyruvate to Lactate and Recycles NAD⁺

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

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Pyruvate Is Reduced to Lactate to Regenerate NAD⁺, Not to Make ATP

Lactate Dehydrogenase Converts Pyruvate to Lactate and Recycles NAD⁺

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

Unlock the rest of this chapter with a free account