Notes for D2.1.15 Control of the cell cycle using cyclins (HL) - IB | RevisionDojo
D2.1.15 Control of the cell cycle using cyclins (HL) Notes
Cyclins Regulate The Cell Cycle
The cell cycle must be tightly controlled to ensure processes occur in the correct order.
Cyclins are regulatory proteins that control progression through the cell cycle by activating enzymes called cyclin-dependent kinases (CDKs).
Different cyclins are specific to different phases of the cell cycle.
How CDKs work
Definition
Cyclins
A group of proteins that regulate the cell cycle by activating cyclin-dependent kinases (CDKs).
How Cyclins Work
Cyclins bind to CDKs, forming an active complex.
This complex phosphorylates target proteins, activating them to perform tasks specific to the cell cycle phase.
Cyclin levels rise and fall in a predictable pattern, ensuring precise control.
Cyclin expression cycle
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Questions
Recap questions
1 of 5
Question 1
Recap question
Consider two cyclins, A and B, with thresholds CA,thresh and CB,thresh at different phases. If CB,thresh is artificially lowered to match CA,thresh, what is the most likely consequence?
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Note
The cell cycle is a series of ordered events that lead to cell growth and division into two daughter cells. It consists of four main phases: G1, S, G2, and M phase.
DefinitionCell CycleThe sequence of events in a cell leading to its division and duplication.
G1 phase: Cell growth and preparation for DNA replication
S phase: DNA replication
G2 phase: Preparation for mitosis
M phase: Mitosis and cytokinesis
AnalogyThink of the cell cycle like a washing machine cycle with specific stages for washing, rinsing, and spinning.
