Notes for D1.2.2 Role of hydrogen bonding and complementary base pairing in transcription - IB | RevisionDojo
D1.2.2 Role of hydrogen bonding and complementary base pairing in transcription Notes
Role of Hydrogen Bonding and Complementary Base Pairing in Transcription
Complementary base pairing (A pairs with U, T pairs with A, C pairs with G, G pairs with C) directs which nucleotides are added during transcription.
Hydrogen bonding between complementary bases therefore ensures the pairing is stable and accurate.
Hydrogen Bonding Is Like Molecular Glue
Hydrogen bonds are weak interactions that hold complementary bases together:
$A-U$ (in RNA) and $A-T$ (in DNA) form two hydrogen bonds.
$C-G$ pairs form three hydrogen bonds.
Hydrogen bonding between base pairsTip
These bonds ensure that RNA polymerase adds the correct nucleotide to the growing RNA strand.
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Questions
Recap questions
1 of 5
Question 1
Recap question
Which rationale best explains why RNA uses uracil (U) instead of thymine (T) for pairing with adenine during transcription?
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