IB Biology Topic D1.1.9 DNA Proofreading Revision Notes (HL)

IB Biology Topic D1.1.9 DNA Proofreading Revision Notes (HL) | RevisionDojo

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DNA Proofreading Keeps Replication Accurate

Imagine copying a 6-billion-letter book by hand.
Even a single typo could change the meaning of a sentence.
DNA replication faces the same challenge: copying billions of base pairs with near-perfect accuracy.

Analogy

Think of DNA polymerase as a meticulous editor, scanning each nucleotide for errors and correcting them on the spot.

How DNA Polymerase Proofreads

DNA polymerase III is the main enzyme that builds new DNA strands in prokaryotes.
It does more than add nucleotides; it also proofreads its own work.

How Proofreading Works

Mismatch detection
1. The enzyme checks each newly added nucleotide.

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Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
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DNA Proofreading Keeps Replication Accurate

Imagine copying a 6-billion-letter book by hand.
Even a single typo could change the meaning of a sentence.
DNA replication faces the same challenge: copying billions of base pairs with near-perfect accuracy.

Analogy

Think of DNA polymerase as a meticulous editor, scanning each nucleotide for errors and correcting them on the spot.

How DNA Polymerase Proofreads

DNA polymerase III is the main enzyme that builds new DNA strands in prokaryotes.
It does more than add nucleotides; it also proofreads its own work.

How Proofreading Works

Mismatch detection
1. The enzyme checks each newly added nucleotide.

Definition

Paywall

(on a website) an arrangement whereby access is restricted to users who have paid to subscribe to the site.

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Note

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam quis nostrud exercitation.

Excepteur sint occaecat cupidatat non proident

Tip

Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
Duis aute irure dolor in reprehenderit in voluptate velit esse cillum.

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A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

IB Biology Topic D1.1.9: DNA Proofreading Notes

A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

DNA Proofreading Keeps Replication Accurate

How DNA Polymerase Proofreads

How Proofreading Works

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

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DNA Proofreading Keeps Replication Accurate

How DNA Polymerase Proofreads

How Proofreading Works

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

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