IB Biology Topic C1.2.11 Oxidation and Decarboxylation of Pyruvate Revision Notes (HL)

IB Biology Topic C1.2.11 Oxidation and Decarboxylation of Pyruvate Revision Notes (HL) | RevisionDojo

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The Link Reaction Connects Glycolysis to the Krebs Cycle

Glycolysis in the cytoplasm breaks glucose down into pyruvate (3C).
The Krebs cycle in the mitochondrial matrix needs acetyl groups (2C).
There is a carbon mismatch, because pyruvate has 3 carbons but the Krebs cycle uses 2-carbon acetyl groups.
The link reaction bridges this gap in the mitochondrial matrix by converting pyruvate (3C) into a 2-carbon acetyl group.
The acetyl group then joins coenzyme A to form acetyl-CoA.

Analogy

The link reaction is a bridge between two locations: glycolysis in the cytoplasm and the Krebs cycle in the mitochondrial matrix.
Without this bridge, the energy stored in pyruvate could not reach the Krebs cycle.

How the Link Reaction Works Step by Step

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Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
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The Link Reaction Connects Glycolysis to the Krebs Cycle

Glycolysis in the cytoplasm breaks glucose down into pyruvate (3C).
The Krebs cycle in the mitochondrial matrix needs acetyl groups (2C).
There is a carbon mismatch, because pyruvate has 3 carbons but the Krebs cycle uses 2-carbon acetyl groups.
The link reaction bridges this gap in the mitochondrial matrix by converting pyruvate (3C) into a 2-carbon acetyl group.
The acetyl group then joins coenzyme A to form acetyl-CoA.

Analogy

The link reaction is a bridge between two locations: glycolysis in the cytoplasm and the Krebs cycle in the mitochondrial matrix.
Without this bridge, the energy stored in pyruvate could not reach the Krebs cycle.

How the Link Reaction Works Step by Step

Definition

Paywall

(on a website) an arrangement whereby access is restricted to users who have paid to subscribe to the site.

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Note

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam quis nostrud exercitation.

Excepteur sint occaecat cupidatat non proident

Tip

Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
Duis aute irure dolor in reprehenderit in voluptate velit esse cillum.

A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

IB Biology Topic C1.2.11: Oxidation and Decarboxylation of Pyruvate Notes

A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

The Link Reaction Connects Glycolysis to the Krebs Cycle

How the Link Reaction Works Step by Step

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The Link Reaction Connects Glycolysis to the Krebs Cycle

How the Link Reaction Works Step by Step

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

Unlock the rest of this chapter with a free account