IB Biology Topic C1.1.15 Competitive Inhibition Revision Notes (HL)

IB Biology Topic C1.1.15 Competitive Inhibition Revision Notes (HL) | RevisionDojo

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A Competitive Inhibitor Blocks the Active Site by Mimicking the Substrate

A competitive inhibitor has a shape similar to the substrate, so it fits into the enzyme's active site.
While it sits there it blocks the substrate from binding, but it cannot be turned into product.
The enzyme is not damaged; it just spends time on a molecule that looks right but does not react.
The more inhibitor is present, the fewer active sites are free, so the reaction runs slower.

Definition

Competitive inhibition

Competitive inhibition is a regulatory mechanism in enzyme-catalyzed reactions where an inhibitor molecule competes with the substrate for binding to the enzyme’s active site.

Definition

Competitive inhibitors

Competitive inhibitors are molecules that resemble the substrate of an enzyme.
They bind to the enzyme’s active site, blocking the actual substrate from binding.

The Inhibitor and Substrate Compete for the Same Site

Because the inhibitor's shape resembles the substrate, both molecules aim for the same active site.

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(on a website) an arrangement whereby access is restricted to users who have paid to subscribe to the site.

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Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Duis aute irure dolor in reprehenderit

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Note

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam quis nostrud exercitation.

Excepteur sint occaecat cupidatat non proident

Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit.

Tip

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
Duis aute irure dolor in reprehenderit in voluptate velit esse cillum.

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A Competitive Inhibitor Blocks the Active Site by Mimicking the Substrate

A competitive inhibitor has a shape similar to the substrate, so it fits into the enzyme's active site.
While it sits there it blocks the substrate from binding, but it cannot be turned into product.
The enzyme is not damaged; it just spends time on a molecule that looks right but does not react.
The more inhibitor is present, the fewer active sites are free, so the reaction runs slower.

Definition

Competitive inhibition

Competitive inhibition is a regulatory mechanism in enzyme-catalyzed reactions where an inhibitor molecule competes with the substrate for binding to the enzyme’s active site.

Definition

Competitive inhibitors

Competitive inhibitors are molecules that resemble the substrate of an enzyme.
They bind to the enzyme’s active site, blocking the actual substrate from binding.

The Inhibitor and Substrate Compete for the Same Site

Because the inhibitor's shape resembles the substrate, both molecules aim for the same active site.

Definition

Paywall

(on a website) an arrangement whereby access is restricted to users who have paid to subscribe to the site.

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Note

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam quis nostrud exercitation.

Excepteur sint occaecat cupidatat non proident

Tip

Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris.
Duis aute irure dolor in reprehenderit in voluptate velit esse cillum.

A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

IB Biology Topic C1.1.15: Competitive Inhibition Notes

A - Unity and Diversity9 subtopics

B - Form and Function10 subtopics

C - Interaction and Interdependence9 subtopics

D - Continuity and Change12 subtopics

A Competitive Inhibitor Blocks the Active Site by Mimicking the Substrate

The Inhibitor and Substrate Compete for the Same Site

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

Unlock the rest of this chapter with a free account

A Competitive Inhibitor Blocks the Active Site by Mimicking the Substrate

The Inhibitor and Substrate Compete for the Same Site

anim nostrud sit dolore minim proident quis fugiat velit et eiusmod nulla quis nulla mollit dolor sunt culpa aliqua

Duis aute irure dolor in reprehenderit

Excepteur sint occaecat cupidatat non proident

Unlock the rest of this chapter with a free account