Structure and Function of Artery Walls
- Arteries are specialized blood vessels that transport blood from the heart to various tissues of the body.
- Their walls are designed to handle high pressures generated during the cardiac cycle.

Layers of the Artery Wall
Artery walls consist of three distinct layers, each with specific components and roles:
- Tunica externa:
- Composition: Tough outer layer of connective tissue containing collagen fibers.
- Function: Provides strength to withstand the high pressures inside arteries.
- Tunica media:
- Composition: Thick layer of smooth muscle and elastic fibers made of the protein elastin.
- Function:
- The smooth muscle regulates the diameter of the artery through contraction and relaxation.
- The elastic fibers allow arteries to stretch and recoil, accommodating pressure fluctuations.
- Tunica intima:
- Composition: A smooth endothelial lining that minimizes friction for blood flow. In some arteries, this layer also includes elastic fibers.
- Function: Provides a low-resistance surface for efficient blood flow.
How Arteries Handle High Pressure
Thick Walls with Elastic Fibers and Collagen
- Elastic fibers can stretch during systole (when the heart pumps blood) and recoil during diastole (when the heart relaxes). This stretch-recoil mechanism ensures that blood pressure is maintained and blood flows smoothly.
- Collagen fibers provide tensile strength to prevent ruptures or aneurysms under high pressure.
Narrow Lumen
- Arteries have relatively narrow lumens, which maintain high pressure and promote fast blood flow.


