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Think of the classic chicken-and-egg problem:
Cohen et al. (1993)
Aim: To investigate the relationship between stress and susceptibility to the common cold.
Method: Participants were exposed to a cold virus after being assessed for stress levels.
Results: Those with higher stress levels were more likely to develop cold symptoms.
Conclusion: While the study suggests stress weakens the immune system, it doesn't rule out the possibility that pre-existing health conditions (which cause stress) could influence the results.