Disease Patterns Reflect Transmission Routes and Uneven Vulnerability
Incidence: is shaped by the pathogen, its transmission route, the physical environment and the population’s exposure and access to prevention or treatment.
Diffusion: follows mosquito habitats, water systems, roads, migration routes and settlement patterns rather than spreading evenly across space.
Impacts: vary with age, pregnancy, immunity, income, health services and the timing of infection in the agricultural or school calendar.
The required contrast: is between one detailed vector-borne example and one detailed water-borne example.
Vector-Borne Disease Requires a Living Carrier
Definition
Vector-borne Disease
Diseases transmitted by living organisms, such as mosquitoes or ticks.
Mosquitoes Connect Infected and Susceptible Hosts
A vector: carries a pathogen between hosts without being the disease itself.
The reservoir: is an infected host from which a mosquito takes up the pathogen during a blood meal.
The incubation period: allows the pathogen to develop inside the mosquito before the next infectious bite.
The cycle: continues when the newly infected person becomes a source for another mosquito.
Note
Break the cycle at different points: Warmer conditions can shorten pathogen development inside the mosquito, but transmission still depends on water, human exposure, vector survival and control measures.
Bed nets block bites, spraying reduces adult mosquitoes and treatment reduces the human reservoir.
Nigeria: Malaria Is Endemic but Uneven
Disease and agent: malaria is caused by Plasmodium parasites and transmitted mainly by female Anopheles mosquitoes.
National burden: Nigeria accounted for about 27% of global malaria cases and 31% of global malaria deaths in the WHO figures used for this case study.
Climate: warm temperatures support parasite development, while seasonal rainfall creates breeding sites and produces peaks after the rains.
Standing water: forms in pools, drains, containers and irrigated areas, especially where drainage is weak.
Population exposure: is high because a large, dense population lives across areas suitable for transmission.
Spatial pattern: is endemic transmission throughout much of the country rather than a single short outbreak.
Demographic and Socio-economic Impacts
Children under five: carry a large share of deaths because they have not yet developed partial immunity.
Pregnancy: raises the risk of maternal anaemia, low birth weight and stillbirth.
Education and work: lose days through repeated illness, while farm labour can fall during the planting season.
Household budgets: lose income and gain treatment costs at the same time.
Responses and Limits
Insecticide-treated nets: reduce contact between mosquitoes and sleeping people.
Indoor residual spraying: kills mosquitoes that rest on treated walls.
Artemisinin-based combination therapy: clears infection and reduces severe illness when diagnosis and treatment are prompt.
Preventive treatment in pregnancy: is delivered through antenatal care, but clinic attendance does not guarantee that every woman receives the full course.
Resistance: reduces effectiveness when mosquitoes survive insecticides or parasites survive medicines.
Case study
Essay use
Use malaria in Nigeria to show that a suitable tropical climate creates transmission potential but social conditions determine the realised disease burden.
Evidence
Nigeria accounted for about 27% of global malaria cases and 31% of global malaria deaths in the WHO figures used for this case.
Analysis
Rainfall and warmth support Anopheles mosquitoes, while drainage, housing, bed-net coverage, treatment access and drug or insecticide resistance create strong variation within the country.
Evaluation
Climate-based explanations are incomplete because households, regions and demographic groups experience unequal exposure and access to prevention, diagnosis and treatment.
Water-Borne Disease Uses Contaminated Water or Food
Definition
Water-Borne Disease
Diseases transmitted through contaminated water.
The Faecal-Oral Route Links Sanitation to Drinking Water
Waste: releases a pathogen from an infected person into the environment.
Contamination: occurs when sewage enters a shared water source through leaks, poor sanitation or flooding.
Exposure: occurs when another person drinks the water or eats food washed or cooked with it.
Renewed transmission: occurs when the newly infected person sheds the pathogen and the loop repeats.
Common Mistake
Name the route precisely: Water-borne does not mean that every infection passes directly from one person to another through water.
The pathogen moves through contaminated water or food, and the route depends on sanitation and shared supply systems.
Haiti: Cholera Spread Through Water and Transport Networks
Disease and agent: cholera is caused by Vibrio cholerae and spreads by the faecal-oral route through contaminated water or food.
Place and date: the outbreak began in Haiti in October 2010 after cholera was introduced into a population with no recent immunity.
Pre-existing vulnerability: the January 2010 earthquake had damaged water and sanitation systems and displaced more than one million people.
Initial spread: followed the Artibonite River from the first cases and then moved through river and road networks.
Scale: about 820,000 cases and 9,792 deaths were reported between October 2010 and February 2019.
Recurrence: confirmed cases returned in 2022 after more than three years without a reported case, exposing the unresolved sanitation gap.
Demographic and Socio-economic Impacts
Acute dehydration: can kill within hours without rapid oral or intravenous rehydration.
Age and vulnerability: shape mortality because children, older people and malnourished patients have less physiological reserve.
Health spending: was diverted to outbreak control while reconstruction needs remained large.
Livelihoods: lost labour time, and fear of infection disrupted movement, trade and trust.
Institutional trust: was damaged after investigations traced the 2010 introduction to a United Nations peacekeeping base.
Responses and Limits
Oral rehydration: prevents many deaths by replacing water and salts quickly.
Vaccination: reduces short-term risk but does not replace safe water and sanitation.
WASH investment: interrupts the route through protected water, sewage treatment, hygiene and surveillance.
Insecurity and displacement: restrict access to treatment and make safe water harder to maintain.
Case study
Essay use
Use Haiti’s cholera outbreak to show how a newly introduced pathogen diffuses through contaminated water, transport networks and pre-existing infrastructure vulnerability.
Evidence
The outbreak began in October 2010 after the earthquake had damaged water and sanitation and displaced more than one million people.
about 820,000 cases and 9,792 deaths were reported to February 2019.
Analysis
Contamination entered a river system and spread through water use and population movement, while recurrence in 2022 after more than three reported case-free years exposed the unresolved sanitation gap.
Evaluation
Treatment centres and oral rehydration reduce mortality during an outbreak, but durable control requires trusted institutions, surveillance and reliable water and sanitation services.
The Two Diseases Require Different Spatial Responses
Malaria control: targets the vector, human-vector contact, the parasite in infected people and the environments where mosquitoes breed.