Reduction of Glycerate-3-Phosphate (GP) to Triose Phosphate (TP)
- The conversion of GP to TP is a two-step process:
- Phosphorylation: ATP donates a phosphate group to GP, forming 1,3-bisphosphoglycerate.
- Reduction: NADPH donates electrons (and hydrogen), converting 1,3-bisphosphoglycerate into TP.
GP to TP Conversion is a pivotal step that transforms a fixed carbon molecule into a sugar that can be used for biosynthesis.
TipRemember: ATP and NADPH are produced in the light-dependent reactions and are essential for driving the Calvin cycle.
Why Triose Phosphate (TP) Matters
- Building Block for Glucose: Two TP molecules can combine to form glucose and other carbohydrates.
- Regeneration of RuBP: Most TP is recycled to regenerate RuBP, ensuring the Calvin cycle continues.
- Versatility: TP can be used to synthesize lipids, amino acids, and other essential molecules.
- Think of ATP as the fuel that powers a car and NADPH as the mechanic that fixes it.
- Both are needed to keep the process running smoothly.
Interdependence of Light-Dependent and Light-Independent Reactions
- The Calvin cycle relies on ATP and NADPH from the light-dependent reactions.
- Without light, ATP and NADPH production stops, halting the Calvin cycle.
- How does the interdependence of these reactions reflect the interconnectedness of biological systems?
- Can you think of other examples where one process depends on another?
Significance of NADPH and ATP in TP Synthesis
NADPH
- Acts as a reducing agent by donating electrons and hydrogen ions.
- Links the light-dependent reactions, where NADP is reduced, to the Calvin cycle.
ATP
- Provides the energy required for phosphorylation and the reduction process.
- Its synthesis during photophosphorylation in the light-dependent reactions ensures that the Calvin cycle has the energy needed for anabolic processes.
Key Points to Remember
- GP is converted to TP using ATP and NADPH.
- TP is a versatile molecule used for glucose synthesis and RuBP regeneration.
- The Calvin cycle is dependent on products from the light-dependent reactions.
- What role does ATP play in the conversion of GP to TP?
- Why is NADPH essential in this process?
- What are the two main fates of TP in the Calvin cycle?


