Mammalian Lungs Are Adapted for Efficient Gas Exchange Through the Alveolar System
- At the center of the mammalian lung’s efficiency is the alveolar system.
- The lungs contain millions of tiny air sacs called alveoli (singular: alveolus), which are the primary sites of gas exchange.
- These alveoli are connected to the outside environment through a branching network of airways, including the trachea, bronchi, and bronchioles.
High Surface Area for Gas Exchange
- The alveoli are tiny air sacs in the lungs where gas exchange happens.
- There are about 300 million alveoli in your lungs, giving them a total surface area of 70 m² (about the size of a tennis court).
- A large surface area means more space for oxygen to enter the blood and carbon dioxide to exit.
- The bigger the surface, the better the diffusion!
- Think of the alveoli as tiny bubbles in a foam.
- The more bubbles you have, the greater the total surface area available for interaction with the air.
Thin Walls for Short Diffusion Distance
- Alveoli walls and the walls of surrounding capillaries are only one cell thick.
- This thin barrier makes it much quicker for gases like oxygen and carbon dioxide to pass through.
- A shorter distance means faster diffusion, so your body can meet its oxygen needs quickly, even during exercise.
Remember, the shorter the diffusion distance, the faster the rate of diffusion. This is why thin walls are a critical adaptation in the lungs.
Common Mistake- Students often confuse the role of capillaries with that of the alveoli.
- Remember, the alveoli provide the surface area for gas exchange, while the capillaries transport the gases to and from the bloodstream.
Surfactant to Keep the Alveoli Open
Surfactant
Surfactant is a lipid-based substance that reduces surface tension in the alveoli, preventing the alveoli from collapsing after exhalation.
- The inside of the alveoli is coated in a thin layer of moisture.
- This helps gases dissolve and diffuse into the blood.
- Surfactant, a special substance produced by cells in the alveoli, reduces surface tension.
- Without surfactant, the alveoli would collapse, and gas exchange would stop. Surfactant keeps them open and ready for action!
- Premature babies often lack sufficient surfactant, which can lead to a condition called neonatal respiratory distress syndrome.
- Treatment involves giving the baby artificial surfactant to help keep their alveoli open.
Surfactant is not only essential for preventing alveolar collapse but also reduces the effort required to inflate the lungs during inhalation.
Dense Capillary Network
- Each alveolus is surrounded by a dense network of capillaries, the smallest blood vessels in the body.
- These capillaries bring blood close to the alveoli, ensuring a constant supply of blood for gas exchange.
- The closer the blood is to the alveoli, the more efficiently oxygen can diffuse into the blood and carbon dioxide can diffuse out.
- Think of the bronchioles as the branches of a tree, with the alveoli acting as the leaves.
- The branching structure ensures that every leaf receives sunlight, just as every alveolus receives fresh air.
Branching Airways for Efficient Air Delivery
- Air enters the lungs via the trachea, which splits into bronchi, then into smaller bronchioles, and finally to the alveoli.
- This branching structure increases surface area and reduces airspeed.
- Slower air speed allows for more efficient gas exchange as the air spends more time in the alveoli, giving oxygen more time to diffuse into the blood.
- Alveoli = Large surface area (300 million, 70 m²)
- Thin walls = Short diffusion distance
- Surfactant = Prevents alveoli collapse
- Capillaries = Bring blood close for efficient gas exchange
- Branching airways = Distribute air evenly
How These Adaptations Work Together
- High Surface Area: The large number of alveoli provides an enormous surface area for diffusion.
- Short Diffusion Distance: The thin walls of alveoli and capillaries minimize the distance gases must travel.
- Moist Surface with Surfactant: Moisture facilitates gas dissolution, while surfactant prevents alveolar collapse.
- Dense Capillary Network: Close contact between alveoli and capillaries ensures efficient gas exchange.
- Branched Airways: The bronchioles distribute air evenly and increase the total surface area for gas exchange.
- How might the adaptations of mammalian lungs for gas exchange reflect the relationship between structure and function in biology?
- Can you think of other examples where form follows function?
- Why is surfactant necessary for efficient gas exchange in the alveoli?
- Describe the role of capillaries in gas exchange at the alveoli.



