The Mitochondrion: Where Aerobic Respiration Happens
The mitochondrion is a double-membrane organelle found in nearly all eukaryotic cells.
It is the site of aerobic cell respiration, the reactions that transfer energy from organic molecules to ATP.
Every structural feature of the mitochondrion relates directly to this function.
Mitochondria are typically sausage-shaped, roughly 1 to 5 µm long and 0.5 to 1 µm wide.
Cells with high energy demands, such as muscle fibres, active-transport epithelia, and sperm cells, contain thousands of mitochondria, while less active cells have fewer.
Outer Membrane: Controlling Entry
The outer membrane is smooth and contains large channel proteins called porins.
Porins let small molecules (pyruvate, oxygen, CO2, ADP, ATP) pass freely between the cytoplasm and the intermembrane space.
Larger molecules and proteins cannot cross without specific transport.
Common Mistake
The outer membrane is not where oxidative phosphorylation occurs.
The outer membrane's job is to contain the organelle and control what enters.
The inner membrane is where the electron transport chain and ATP synthase sit.
Inner Membrane and Cristae: The Site of Oxidative Phosphorylation
The inner membrane is folded into structures called cristae (singular: crista).
These folds massively increase the surface area for the electron transport chain (ETC) and ATP synthase.
More cristae means more surface area, which means more ATP production.
Cells with very high energy demands, like cardiac muscle cells, have mitochondria with densely packed cristae.
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