A calmer way to choose an IA topic (without chasing “perfect”)
At some point, every IB Chemistry student has the same quiet panic: you want an IA idea that sounds original, but also works in the real world. Not “works” as in the reaction happens once. Works as in: you can control variables, repeat trials, collect enough data, and write something that looks like science instead of a diary entry.
The best IB Chemistry IA topics don’t come from trying to impress the internet. They come from noticing a small, testable question inside a bigger interest: medicine, dentistry, engineering, the environment, or biomedical tech. And then shrinking it until it fits on a lab bench.
This guide gives you a long menu of IB Chemistry IA ideas for 2025, sorted by major and anchored to syllabus-friendly themes (acids and bases, kinetics, redox, bonding, organic chemistry, materials). You’ll also find a quick checklist for choosing a topic that’s safe, measurable, and grade-friendly.
If you want a home base while you decide, start with the official IB Chemistry hub on RevisionDojo: IB Chemistry resources.

The 60-minute IA topic checklist (save yourself weeks)
Before you fall in love with an idea, run it through this checklist. It’s the difference between a topic that “sounds good” and a topic that scores.
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Can you measure the dependent variable precisely? (colorimeter/spectrophotometer, titration volume, mass change, conductivity, pH probe, time)
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Can you control key variables (temperature, concentration, surface area, light intensity, stirring, time)?
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Can you do 5+ data points for the independent variable and 3+ repeats per point?
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Is it safe and allowed in your school lab (no restricted reagents, no risky synthesis, no complex biological samples)?
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Does the chemistry connect clearly to core IB Chemistry concepts (equilibrium, kinetics, redox, structure, intermolecular forces)?
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Can you explain your method and uncertainties with honesty and detail?
When you’re ready to align your write-up with what examiners actually reward, use RevisionDojo’s examiner-written guide: IB Chemistry Internal Assessment Guide.
Best Chemistry IA ideas in 2025 (sorted by major)
Below, each major includes practical topic directions. For every idea, the secret is the same: turn it into one tight research question with a measurable outcome and a reason the chemistry behaves the way it does.
Medicine (and everyday biochemistry)
Medicine topics are popular in IB Chemistry because the materials are accessible (tablets, juices, vitamins) and the chemistry is rich (hydrolysis, buffers, redox titrations, kinetics).
pH and hydrolysis of aspirin (acetylsalicylic acid)
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Idea: How does pH affect the hydrolysis rate of aspirin in aqueous solution?
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Why it works: Clear acid-base reasoning and kinetics. You can measure product formation or concentration change over time.
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Helpful syllabus support: acid-base foundations via R3.1 Proton transfer reactions.
Vitamin C content in juices (titration vs label)
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Idea: Determine vitamin C concentration in fresh vs bottled juices using a redox titration and compare with packaging claims.
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Why it works: Strong data tables, repeatable endpoint, clear evaluation of uncertainty.
Dissolution rates of tablets in different pH environments
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Idea: How do tablet formulations dissolve differently in pH 2, 4, 7, 9 buffer solutions?
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Why it works: Practical kinetics with controlled variables.
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Connect it to kinetics: R2.2 How fast? The rate of chemical change.
Light exposure and stability of common medications
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Idea: How does light intensity or wavelength affect degradation of a medication or dye model compound?
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Why it works: You can measure absorbance changes with time if your lab has a colorimeter.
Storage conditions and “shelf-life” behavior (model study)
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Idea: Compare stability of vitamin C solutions under temperature/light/storage conditions.
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Why it works: Doesn’t require restricted chemicals, but still shows real chemical reasoning.
Solubility of a “drug model” in different solvents
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Idea: How does solvent polarity affect solubility of caffeine or another accessible compound?
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Why it works: Great link to intermolecular forces and separation techniques.
Chelation and heavy metal removal (EDTA model)
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Idea: Investigate how EDTA concentration influences removal of metal ions from solution.
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Why it works: Strong quantitative analysis, clear chemical mechanism.
Antacids as neutralization systems
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Idea: Compare how different antacids neutralize acid (rate, capacity, or both).
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Why it works: Classic IB Chemistry acid-base with easy measurement and strong evaluation.
If you want to see what high-quality IA execution looks like in real student work, browse: IB Chemistry IA Examples.
Dentistry (acids, enamel, and materials)
Dentistry topics are basically IB Chemistry dressed in a human story: acids, buffers, mineral equilibrium, and corrosion.
Fluoride and enamel hardness (model approach)
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Idea: Investigate how fluoride treatment impacts surface hardness of enamel substitutes (or lab-safe calcium phosphate models).
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Tip: If you can’t use real enamel, use a consistent calcium carbonate-based model and discuss limitations clearly.
Mouthwash pH and erosion potential
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Idea: Compare pH of mouthwashes and quantify their acid content via titration.
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Why it works: Simple method, big discussion around buffering and formulation.
Saliva pH shift after acidic drinks (buffer behavior)
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Idea: How does exposure to acidic beverages change simulated saliva pH over time?
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Why it works: Great opportunity to explain buffers and equilibrium.
Corrosion of dental amalgam substitutes
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Idea: Measure corrosion rates of safe metal samples (not actual amalgam) under different pH.
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Why it works: Electrochemistry + real-world application.
Toothpaste abrasiveness (materials angle)
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Idea: Compare relative abrasiveness of toothpaste formulations using a consistent surface and a measurable mass loss or scratch metric.
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Why it works: Materials chemistry with controlled testing.
Whitening agents and oxidation chemistry (safe proxy)
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Idea: Explore oxidation strength of peroxide-based products using dye decolorization as a proxy.
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Why it works: Clear redox reasoning and measurable color change.
To strengthen your acid-base theory explanations (and avoid vague statements), pair your research with focused notes like Conjugate acid-base pairs (R3.1.2) notes.
Engineering (industry-style chemistry you can actually test)
Engineering-flavored IB Chemistry topics tend to score when they’re framed as optimization: best catalyst, best inhibitor, strongest polymer, most efficient process.
Catalyst efficiency vs temperature
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Idea: How does temperature affect catalyst performance in a controlled reaction?
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Why it works: Strong kinetics graphs and Arrhenius-style discussion.
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Practice the theory: R2.2 questionbank.
Corrosion rates of metals in acidic solutions
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Idea: Compare mass loss or voltage changes for different metals in acid.
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Why it works: Great data trends, strong evaluation, real engineering relevance.
Pressure effects on gas reactions (simulation model)
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Idea: Model pressure effects using gas syringes and equilibrium-friendly systems (or a well-justified simulation with limitations).
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Why it works: If done carefully, it links to Le Châtelier’s principle and kinetics.
Tensile strength of polymers (DIY materials testing)
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Idea: Compare tensile strength of polymer strips under standardized loading.
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Why it works: Clear method, good graphs, strong materials discussion.
Thermal conductivity of building materials (comparative study)
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Idea: Compare heat transfer rates through materials under controlled conditions.
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Why it works: Clean data if you standardize thickness and temperature gradient.
Alloy composition and properties (model alloys)
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Idea: Relate composition to conductivity or corrosion resistance using safe metals.
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Why it works: Strong link to bonding and metallic structure.
Biodiesel yield with different catalysts
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Idea: Compare biodiesel production efficiency using different catalysts (if allowed and safe).
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Why it works: Organic chemistry with clear yield calculations.
Environmental science (chemistry that tells a bigger story)
Environmental IB Chemistry IAs shine when students measure something local: water, soil, filtration, plastics, fertilizers. The trick is to avoid being too broad.
Heavy metals in water (colorimetric analysis)
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Idea: Use colorimetry to determine concentration changes or removal efficiency.
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Why it works: Clear calibration curve, strong uncertainty discussion.
Acid rain effect on soil pH and nutrient availability
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Idea: Model acid rain using dilute acids and measure soil pH changes and buffering capacity.
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Why it works: Strong acid-base reasoning and environmental relevance.
Household water filtration effectiveness
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Idea: Compare activated carbon, sand, cloth, or commercial filters using turbidity, conductivity, or dye removal.
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Why it works: Repeatable, measurable, and easy to evaluate limitations.
Biodegradability of plastics (simulated conditions)
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Idea: Compare mass loss or tensile strength change after exposure to controlled conditions.
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Why it works: Materials chemistry with long-term data if you plan early.
Fertilizers and algal bloom chemistry (safe proxy)
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Idea: Model nitrate/phosphate impact using safe nutrient solutions and measure changes like conductivity or colorimetric indicators.
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Why it works: Quantifiable and discussion-rich.
Oil pollution and oxygen solubility (proxy measurement)
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Idea: Investigate how an oil layer affects dissolved oxygen change over time (with probes if available).
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Why it works: Strong intermolecular and physical chemistry explanations.
pH and heavy metal mobility (soil leaching model)
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Idea: Test how pH changes leaching of metal ions from soil substitutes.
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Why it works: Great link to equilibrium and solubility concepts.
Pesticide degradation comparisons (model compounds)
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Idea: Compare breakdown rates under light/temperature using safe dyes or proxy molecules.
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Why it works: Controlled kinetics without hazardous chemicals.
Composting and soil chemistry change
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Idea: Track pH and conductivity changes during composting under controlled conditions.
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Why it works: Data-rich if you measure consistently.
Catalytic converters and emission reduction (catalyst model)
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Idea: Model catalytic breakdown of a safe gas or use a lab-safe proxy reaction.
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Why it works: Shows catalysis understanding with a realistic storyline.
Pharmaceutical sciences (when “medicine” becomes formulation)
Pharma-style IB Chemistry is about formulation variables: pH, solvent, coating, light, preservatives. It’s more controlled than it looks.
Stability under storage conditions (temperature/light)
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Idea: Compare degradation of a vitamin solution or dye model under different storage setups.
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Why it works: Repeatable time-series data.
Preservatives and shelf-life (model system)
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Idea: Compare oxidation rate changes with different preservative concentrations.
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Why it works: Strong variable control and meaningful evaluation.
pH and absorption of weak acid drugs (model equilibrium)
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Idea: Model ionization vs pH and connect to solubility differences.
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Why it works: Great acid-base equilibrium narrative.
Tablet coatings and dissolution kinetics
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Idea: Compare dissolution profiles for coated vs uncoated tablets across pH.
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Why it works: Clear graphs and strong kinetics.
Vitamin C stability vs temperature (Arrhenius-friendly)
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Idea: Determine degradation rate constants at different temperatures.
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Why it works: High-level analysis without dangerous reagents.
Drug and food acids interaction (model)
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Idea: Test how acidity changes solubility or reaction rate in a controlled system.
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Why it works: Applied acid-base chemistry.
Buffering agents in pharmaceutical solutions
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Idea: Compare buffer capacity of different buffer systems at similar pH.
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Why it works: Very “IB” if you do it with careful calculations and uncertainty.
Antacids: neutralization capacity and reaction rate
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Idea: Compare brands by total neutralization (titration) and speed (time to pH threshold).
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Why it works: Two dependent variables can be elegant if managed carefully.

Biomedical engineering (materials that must behave in the body)
Biomedical topics work well in IB Chemistry when you focus on a single measurable property: degradation rate, swelling, strength, ion release, adsorption.
Biomaterials chemical properties (polymer focus)
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Idea: Compare polymer water absorption or swelling ratio in saline vs water.
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Why it works: Simple measurements, strong intermolecular forces discussion.
Biodegradable polymer degradation rates
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Idea: Track mass loss or tensile strength reduction of biodegradable polymers under controlled conditions.
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Why it works: Great data trends if you plan early.
Sterilization methods and material properties (safe simulation)
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Idea: Compare heat/UV exposure and its effect on polymer brittleness or mass.
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Why it works: Clear variable control and evaluation.
pH and drug release from polymer matrices (model beads/gel)
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Idea: Use dye-loaded gels and measure diffusion/release vs pH.
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Why it works: Strong method, strong graphs, strong discussion.
Hydrogels for wound dressings: absorption and crosslinking
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Idea: How does crosslinking concentration affect water uptake and mechanical stability?
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Why it works: Classic materials chemistry with clean data.
Antimicrobial coatings (adsorption model)
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Idea: Compare adsorption of a safe antibacterial agent onto surfaces, measured via colorimetry.
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Why it works: Quantitative, controlled, and discussion-rich.
Nanomaterials for delivery (safe proxy approach)
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Idea: Model surface area effects using different particle sizes (non-hazardous) and adsorption of dye.
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Why it works: Lets you discuss nanoscale behavior without risky materials.
How to turn an idea into a high-scoring research question
Most IB Chemistry IA ideas fail for a boring reason: the research question is either too big, too vague, or not measurable.
Use this template:
“How does [independent variable with range] affect [dependent variable with units] of [chemical system], under [controlled variables]?”
Examples:
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“How does pH (2.00, 4.00, 6.00, 8.00, 10.00) affect the hydrolysis rate constant of aspirin, determined by …?”
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“How does temperature (15°C to 55°C) affect vitamin C concentration in solution, determined by titration volume of …?”
When you start collecting data, align your processing and graphing with a rubric-first mindset. RevisionDojo’s breakdown here is practical and specific: 2.2 Data analysis (IB Chemistry IA).

Where RevisionDojo fits into your IA and exam prep
Your IA is coursework, but it quietly trains the same muscles you need for exams: variables, uncertainty, mechanisms, and structured explanations. That’s why the best strategy is to connect your IA topic to your revision system.
Here’s a simple workflow many strong IB Chemistry students use:
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Use the Study Notes and Lessons to learn the underlying chemistry clearly.
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Use Flashcards to lock in definitions, relationships, and required equations.
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Use the Questionbank to practice exam-style reasoning on the exact unit your IA depends on.
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Use AI Chat to pressure-test your logic: “What variable am I not controlling?” “What is my chemical rationale for the trend?”
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Use the Grading tools to check whether your writing matches IB criteria, not just teacher preference.
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Add Mock Exams and Predicted Papers closer to exam season to convert understanding into speed and accuracy.
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If you’re stuck, the Coursework Library (exemplars) and Tutors help you move forward without guessing.
Start with these relevant RevisionDojo pages:
Closing: pick the topic that will still feel doable on a tired Tuesday
A strong IB Chemistry IA topic isn’t the one that sounds like a journal article title. It’s the one you can repeat, measure, explain, and defend with clean chemistry logic. If you’re torn between two ideas, choose the one with simpler variables and more reliable measurement. Your future self will thank you when it’s time to process data and write the evaluation.
When you’re ready to turn a promising idea into a top-scoring investigation, use RevisionDojo as your system: learn the content with notes and lessons, practice with the Questionbank, sanity-check your reasoning with AI Chat, and refine your write-up with the Chemistry IA Grader and Coursework Library exemplars. Start here: IB Chemistry resources.